Donor Testing and Screening

Donor Testing

 Excellence in Testing

We Test and Screen Donors More Than Others

Seattle Sperm Bank tests and screens donors more than any other sperm bank. We pioneered the Genetic Carrier Screening, and have continuously expanded our screening panels on various levels.

Initially our donors are selected by our sperm bank staff, based on a number of parameters:

 

  • Sperm Quality
  • Age
  • Personality
  • Education
  • Criminal Background Check
  • 4 Generation Family Health History

 

Further Screening Includes Blood and Urine Analysis

Physical Exam every 6 months (including EKG)

Chemistry Panel

Complete Blood Count

Urinalysis

ABO-Rh Blood typing

HIV

HTLV I/II

Hemoglobin Fractionation

Hepatitis B Surface Antigen

Hepatitis B Core Antibody

Hepatitis C Viral Antibody

Syphilis

CMV IgG/IgM

Chlamydia

Gonorrhea

The Genetic Testing We Do Includes The Following:

  • 4 generation family medical history, which is reviewed by a trained genetic specialist and a medical doctor (all donors)
  • Cystic Fibrosis screening
    →  Up to 97 mutations on donors with optional advanced testing.
    →  32 standard mutations tested on all donors include:
G85E
R117H
R334W
R347H
R347P
2184delA
3659delC
A455E
∆I507
∆F508
V520F
G542X
3905insT
3849+10kb C→T
S549N
S549R
G551D
R553X
R560T
1078delT
R1162X
W1282X
N1303K
394delTT
3876delA
621+1 G→T
711+1 G→T
2789+5 G→A
1717-I G→A
1898+1 G→A
2183AA→G
3120+1 G→A
Chromosome analysis (all donors)
Spinal Muscular Atrophy (SMA) (all donors)
Sickle Cell Disease. For all donors a Hemoglobin Fractionation analysis is done to detect this indirectly.
Thalassemia (all donors). A Hemoglobin Fractionation analysis is done to detect this indirectly. Please contact us if you would like to have your donor genetically screened for carrier status.
Bloom Syndrome (donors with Azhkenazi Jewish Ancestry)
Canavan disease (donors with Ashkenazi Jewish ancestry)
Familial Dysautonomia (donors with Ashkenazi Jewish ancestry)
Fanconi Anemia type C (donors with Ashkenazi Jewish ancestry)
Gaucher disease (donors with Ashkenazi Jewish ancestry)
Niemann-Pick type A disease (donors with Ashkenazi Jewish ancestry)
Tay-Sachs disease (donors with Ashkenazi Jewish or French Canadian ancestry)

Extended Genetic Testing

Seattle Sperm Bank is proud to offer Counsyl’s Foresight Carrier Screen, which includes testing for 175 conditions.

Over the years, we have expanded our genetic testing of donors as genetic knowledge and technology continue to advance. As a result, not all donors have been tested for the same conditions or with the same methods. However, all donors have undergone screening and testing for the conditions listed here, if not more.

Extended Genetic Testing

If patients know they are carriers for conditions not covered by our testing, we are very accommodating in helping them get a donor tested for that condition. Our online Donor Search function has an advanced search tool where carrier screening results can be used for filtering our available donors, based on carrier screening results.

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